The Twins shortstop felt tightness in his hamstring while scoring from second base in the eighth inning Sunday, and Plouffe was held out of the starting lineup Monday and Tuesday in favor of Matt Tolbert.
"He went out and ran sprints, he said he felt OK," McWane said. "We're just going to see what he can do the next couple days and try to make a decision."
But with all the injuries the Twins have dealt with lately, manager Ron Gardenhire does not want to go too long with Plouffe on the bench and unavailable to play.
One way or another, he expects a roster move after Wednesday's game.
"We can't keep [going] day to day [with] stuff, it's not helping me a bit. We need either 'yes' or 'no'," Gardenhire said. "We'll see where Plouffe is at. Probably a 'yes' or 'no', I'm not going to give it a 'Let's wait and see.'" -- Jordan Schelling