Span had been set to hit leadoff and start in center field, but as batting practice was winding down, the Twins announced Span would be benched for precautionary reasons.
"Span had a little bit of a sore hammy after [Monday's] game," manager Ron Gardenhire said Tuesday. "It's no big deal."
It still didn't sound like a big deal, as the Twins said Span would be available to pinch-hit. Erik Komatsu, who is hitting .240 this season, replaced Span for the second straight day.
Span is hitting .292 and has a .358 on-base percentage in 34 games this year. His presence is especially missed against the Tigers, against whom he's had great success in his career. Span hits .353 (77-for-218) with eight doubles, eight triples, 23 RBIs in 53 games against Detroit.