Doumit suffered a right calf strain, and the Twins announced it would require a stint on the 15-day disabled list. Manager Ron Gardenhire said he believed the injury happened in the seventh inning, when Doumit got excited behind the plate about escaping a two-on, two-out jam.
"After we struck out [Alex] Avila, I think he jumped up and shook his hand, and I think that's when he popped his calf," Gardenhire said. "But he had been having some cramps in his calf, and Doumit was kind of fighting [through it]."
Outfielder Ben Revere will be recalled from Triple-A Rochester before Thursday's game.
Doumit was 2-for-3 with an RBI and a run scored before exiting. He is hitting .264 with five home runs and 24 RBIs. One of his biggest impacts comes in spelling Joe Mauer and preventing the former American League Most Valuable Player from the wear and tear of catching every day behind the plate.
Gardenhire said Doumit will undergo an MRI, with more information coming Thursday.
Anthony Odoardi is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.