Minnesota will recall right-handed reliever Kyle Waldrop to take his place on the roster. Waldrop will be available for Friday night's game against the Royals after Thursday's off-day.
Manship, 27, posted a 10.27 ERA with five strikeouts, three walks and four homers allowed in eight appearances totaling 10 2/3 innings.
"Jeff has been kind of scuffling," manager Ron Gardenhire said. "We've all seen that. He hasn't been able to get through innings. All his pitches are blending together. So he's got to get back to slowing the ball down and locating the ball better. So we'll send him back down there to get going."
Waldrop, meanwhile, has pitched well at Triple-A Rochester, with a 1.26 ERA, five strikeouts and five walks in 14 1/3 innings. The 26-year-old was likely to make the club out of Spring Training, but suffered a right elbow strain in late March.
"Waldrop is back healthy," Gardenhire said. "He's throwing the ball well. We'll see how he does up here."