Span actually has a reverse platoon split, as he's hit better against lefties than righties in his career (.290 vs. .283, respectively), but Price is especially tough on lefties.
Left-handed hitters have a .198 average against Price over his career while right-handers have a .236 average.
"I don't ever fear it with Denard, righties or lefties, but if you're going to give him a day off, this is a good guy to give him one," Twins manager Ron Gardenhire said.
With Span out of the lineup, Ben Revere started in center field, while Darin Mastroianni got the start in right field.
"Mastroianni's been swinging pretty good," Gardenhire said. "I know he can swing against lefties, so I'll give him a run at it."