Hendriks will be starting in place of right-hander Nick Blackburn, who was outrighted to Rochester on Monday after struggling to a 7.39 ERA in 19 starts this season.
"I'm happy to be back up here, so hopefully we can move forward and stay up here," Hendriks said. "After I got sent back down, I told myself to just stop screwing around with my mechanics and get back to what I was doing in Spring Training. Step back, get set and throw. It was helping me out."
Hendriks was impressive in Rochester, posting a 2.20 ERA in 16 starts. He also struck out 82 and walked 28 in 106 1/3 innings. His last start came Friday, when he allowed four runs on seven hits over seven innings.
Hendriks, though, has had trouble translating his Minor League success to the Majors, as evidenced by his career 6.71 ERA in 12 big league starts. He's 0-5 with a 7.04 ERA in eight outings with the Twins this season.
"He's obviously had his struggles up here, but he's done very well in Triple-A," Twins manager Ron Gardenhire said. "Whether he can make the jump up here and separate remains to be seen. We'll get another opportunity to look at him. He's done what he's supposed to in Triple-A and they've actually told me he's the best pitcher in that league. And that's saying an awful lot. There's a lot of young arms in that league."